[BioC] methylumi
Noemi Andor
Noemi.Andor at campus.lmu.de
Thu Jun 24 00:05:49 CEST 2010
Hello everybody,
I'm currently working with Methylation data. Three data types:
IlluminaDNAMethylation_OMA003_CPI_CPI,
IlluminaDNAMethylation_OMA002_CPI_CPI
both from Illumina Golden Gate BeadArray platform
and
Illumina Infinium Human DNA Methylation 27 platform
After several trials, I finally succeeded loading the data into R(after reorganizing it into one single file - like in the example-data from the methylumi-package in R)
But how do I get the mappings of the probe, e.g.
Composite Element Cy3 Cy5 Detection Pvalue
cg08367223 9.75030715328155 51.3125 3.68E-38
Interpretation: Cy5/Cy3 > 0 --> location x is hypermethylated,
But where is this location x? Are there some mappings, similar to cdf-files from Affy-data, or is the location somehow encoded in the Composite element.
The OMA003-platform for instance has comosites such as:
SOX17_P303_F
this means, it refers somehow to the SOX17 - gene, P303 - position 303 starting from startcodon? F?
would be very greatfull for some tipps.
thank's,
Noemi
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