[BioC] Which application to start BioConductor?
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Wed Jan 6 23:11:53 CET 2010
On Wed, Jan 6, 2010 at 4:35 PM, cihan inan <cihan253 at gmail.com> wrote:
> Well I am a biology student at university. and next year I will be a master
> student. I am planning to be in bioinformatics department. that's why I need
> to learn as much as I can. But at first I want to learn analysis about
> microarrays. from beginning to the end. normalisation etc... I have 6
> months and I think it is enough to learn a lot of think about microarrays.
No simple answer, but try this after installing Bioconductor.
Select the 1st one (eg. the primer).
It deals with getting your feet wet w/ affy arrays (some
normalization/quality control stuff, too). Check out the papers in the
References section too for more info.
As you get going, you'll quickly find the need to use limma as well: a
package to call differentially expressed genes between samples. It's a
very flexible, which is great, but also a bit complex since it's so
Load the library and fire up its user's guide
Lots of good references in its Bibliography.
6 months is *just about* enough time to get through that user guide
plus refs (and their refs) + getting comfortable w/ R and Bioconductor
... you might find you'd like even more time, though ... let us now
Graduate Student: Computational Systems Biology
| Memorial Sloan-Kettering Cancer Center
| Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact
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