[BioC] How does the rank product calculate the fold change

Hildebrand, Georg georg.hildebrand at mpibpc.mpg.de
Sat Feb 20 22:27:39 CET 2010


Hi,

my question is accordin to the library(RankProd) package
maybe this question is very easy, but i was not able to find an
satisfying answer.

I created a list of diff. expressed genes with the Rank product package.
Everything works well, but in the output of the topgenes() function i
do not understand how the fold change is processed.
Has anyone a hint?

It is not just the difference of the mean like in limma. Even in the
papers of breitling there is no good hint.


best regards ,
Georg Hildebrand
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E-mail: georg.hildebrand at mpibpc.mpg.de



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