[BioC] GSEA, topGO, GOstats...? what's a good way to look at GO over-representation?
J.delasHeras at ed.ac.uk
J.delasHeras at ed.ac.uk
Mon Feb 8 17:29:48 CET 2010
Dear list,
I have a few gene lists derived from a human Illumina expression
array. I just have Illumina IDs, I have gene names, and I have entrez
gene IDs I obtained for them.
I would like to analyse the list to look for over-representation of
some category, probably using gene ontologies.
I see there are several packages that seem to address this, although
when I look at the examples I get the feeling they were designed with
Affy arrays in mind and depend on an Affy array design...
I am sure I am not the only one wanting to do this type of work on
non-Affy arrays... I would appreciate a nudge towards the right
package, or a way to "persuade" it to work with non-Affy array data,
after all I imagine that all the array design is used for is the
definition of teh genelists/universe and retrieval of the relevant GO
ids.
Thank you for any helpful comments.
Jose
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