[BioC] Get gene expression data by averaging probes corresponding to the gene?
Gordon K Smyth
smyth at wehi.EDU.AU
Fri Apr 2 00:43:24 CEST 2010
Dear anonymous,
The avereps() function the limma package does exactly this.
Best wishes
Gordon
> Date: Thu, 01 Apr 2010 15:41:52 +0800 (CST)
> From: "697820169" <697820169 at mail.ndmctsgh.edu.tw>
> To: bioconductor at stat.math.ethz.ch
> Subject: [BioC] Get gene expression data by averaging probes
> corresponding to the gene?
>
> I am trying to do a pooled microarray analyze with arrays
> of different platform. In order to have a comparable data,
> I have come to the idea to convert the probes in each array
> to corresponding gene symbols, and use these gene expression
> data instead of probe expression as the data to analyze.
>
> I've tried to find a function of averaging probes to
> corresponding genes, but found nothing that meet my need.
> I have done a few google searches like "bioc average probe
> intensity to gene", "bioconductor average probe to gene",
> etc... and came up with no usable information.
>
> If anyone can give me a hint where I can find the function I
> need, I will very much appreciate.
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