[BioC] Get gene expression data by averaging probes corresponding to the gene?

Sean Davis seandavi at gmail.com
Thu Apr 1 12:49:37 CEST 2010


On Thu, Apr 1, 2010 at 3:41 AM, 697820169
<697820169 at mail.ndmctsgh.edu.tw> wrote:
> I am trying to do a pooled microarray analyze with arrays
> of different platform. In order to have a comparable data,
> I have come to the idea to convert the probes in each array
>  to corresponding gene symbols, and use these gene expression
> data instead of probe expression as the data to analyze.
>
> I've tried to find a function of averaging probes to
> corresponding genes, but found nothing that meet my need.
> I have done a few google searches like "bioc average probe
> intensity to gene", "bioconductor average probe to gene",
> etc... and came up with no usable information.
>
> If anyone can give me a hint where I can find the function I
> need, I will very much appreciate.

Have a look at the aggregate() function.

Sean



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