[BioC] Problem with duplicateCorrelation in LIMMA
York Lee
yorklee70 at gmail.com
Tue May 19 22:40:58 CEST 2009
I have four columns of log2-transformed ratio data
(http://ifile.it/ija65rq). I want to analyze it with LIMMA, but stuck
with duplicateCorrelation:
> library(limma)
> M <- read.delim('M.txt')
> design <- cbind(c(-1, 0, -1, 0), c(0, -1, 0, -1))
> corr <- duplicateCorrelation(M, design=design, spacing=5776, ndups=3)
Error in glmgam.fit(dx, dy, start = start, tol = tol, maxit = maxit,
trace = trace) :
Starting values give negative fitted values
Does anybody has similar experience and any hints to share?
York
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