[BioC] Annotation for Mouse 430 2.0 and Human Genome U133 Plus 2.0 Arrays

Maria Stalteri m.stalteri at mail.cryst.bbk.ac.uk
Wed Jan 28 13:30:51 CET 2009

Hi Dorothy,

The Mouse 430A 2.0, Mouse 430 2.0, and MOE430A are different arrays.

As I understand it, the hgu133plus2 and hgu133plus2.db packages contained 
the same information, only in different formats. But only the 
hgu133plus2.db format  appears to be included in the current release 
(2.3) of  Bioconductor.

If you are asking whether there have been any changes in the annotations 
for the current release (2.3) compared to earlier releases, the 
annotations are always changing, ad you can expect differences of the 
order of maybe 5-10%, sometimes more, from one release to the next. That 
is because the underlying databases that are the sources of the 
annotations - EntrezGene, UniGene and RefSeq, for example - are constantly 

Hope this answers your question.


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