[BioC] GSEA to discover co-regulated genes
Paul Geeleher
paulgeeleher at gmail.com
Wed Jan 21 12:56:02 CET 2009
Hi All,
I've been following the instructions here:
http://www.bioconductor.org/workshops/2007/seattle_bioc_intro_nov_07/folder.2007-11-30.5595085375/
to find dysregulated kegg pathways in a dataset. What I'm now
wondering is if I can use the same methodology to find co-regulated
genes / genes with common transcription factors?
I'd assume its simply of redefining the gene set
gsc <- GeneSetCollection(eset, setType = KEGGCollection())
to
gsc <- GeneSetCollection(eset, setType =
CoRegulatedGenesOrSomeFunctionLikeThat())
I suppose what I'm asking is if such a gene set exists in
Bioconductor? And if not can this be done somewhere else?
Thanks.
--
Paul Geeleher
Department of Mathematics
National University of Ireland
Galway
Ireland
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