[BioC] GSEA to discover co-regulated genes

Paul Geeleher paulgeeleher at gmail.com
Wed Jan 21 12:56:02 CET 2009


Hi All,

I've been following the instructions here:

http://www.bioconductor.org/workshops/2007/seattle_bioc_intro_nov_07/folder.2007-11-30.5595085375/

to find dysregulated kegg pathways in a dataset. What I'm now
wondering is if I can use the same methodology to find co-regulated
genes / genes with common transcription factors?

I'd assume its simply of redefining the gene set

gsc <- GeneSetCollection(eset, setType = KEGGCollection())
to
gsc <- GeneSetCollection(eset, setType =
CoRegulatedGenesOrSomeFunctionLikeThat())


I suppose what I'm asking is if such a gene set exists in
Bioconductor? And if not can this be done somewhere else?

Thanks.

-- 
Paul Geeleher
Department of Mathematics
National University of Ireland
Galway
Ireland



More information about the Bioconductor mailing list