[BioC] Timecourse package

[Yu Chuan Tai]

Hi Priscila,

Am I right that your data have 2 time points, each with a pair of dye-swap 
experiments? For each biological replicate, was it sampled repeatedly 
over time? Looks like timecourse can be used, as long as it's 
of longitudinal design. You can just flip the log2 ratio for Control X T 
so that you get two replicated vectors of log2 ratios.

Best,
Yu Chuan

On Tue, 17 Feb 2009, Priscila Grynberg wrote:

> Dear BioCs,
> I'd like to know if it's possible to analyse two-channel microarray data
> using the timecourse package. I read the pdf, and the examples use Affy
> data.
>
> I'm working with 70-mer oligonucleotide microarray slides. Here is my
> experimental design:
>
> Control X T1 (Biological Replicate 1)
> T1 X Control (Biological Replicate 1)
>
> Control X T1 (Biological Replicate 2)
> T1 X Control (Biological Replicate 2)
>
> Control X T2 (Biological Replicate 1)
> T2 X Control (Biological Replicate 1)
>
> Control X T2 (Biological Replicate 2)
> T2 X Control (Biological Replicate 2)
>
> My control sample is really important for my analysis.
>
>
> --
> Priscila Grynberg, B.Sc., M.Sc.
> Doutoranda em Bioinform??ica (Bioinformatics D.Sc student)
> Laborat??io de Gen??ica Bioqu??ica
> Universidade Federal de Minas Gerais
> Tel: +55 31 3409-2628
> CV: http://lattes.cnpq.br/8808643075395963
>
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