[BioC] Normalization of bi-modal expression data

[Marcelo Laia]

2009/2/11 Balasubramanian Ganesan <bala.g at aggiemail.usu.edu>:
> Dear allWe have developed a method to normalize such bimodal expression data
> called RMA-MS (RMA multispecies).
> And yes, we do find that the number of genes found to be significant
> increases with RMA-MS vs traditional RMA, with much smaller q-values for the
> RMA-MS-normalized data.
> Dear Christian
> If you are interested we will be happy to share this procedure with you.
> Let me know.
>
> Stevens, John R., Balasubramanian Ganesan, Prerak Desai, Sweta Rao, and Bart
> C. Weimer. 2008. Statistical issues for normalization of multi-species
> microarray data. Proceedings of the Nineteenth Annual Kansas State
> University Conference on Applied Statistics in Agriculture.
>
> BALA.


Dear Ganesan,

I'm very interested in your bi-modal normalization method. I would
like to apply it on one color nylon membrane array data. Please, could
you share it with me? The paper and any how to is very welcome.

Thank you very much

Marcelo


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