[BioC] Overlapping genes in subsets of lists
Heike Pospisil
pospisil at zbh.uni-hamburg.de
Wed Oct 8 14:34:55 CEST 2008
Hello there,
I have 100 lists of differentially expressed genes, and I am trying to find
genes overrepresented in these 100 lists (I call them a 'cluster of genes').
What's worse, I expect not only one cluster of genes, but three or four or
five of them. That is why, a simple intersection() will not help. I wish to
had a function that can select all genes which appear in 100% of 33 lists of
genes (cluster 1), all genes which appear in 100% of 22 lists (cluster 2) and
all genes which appear in 100% of the remaining 45 lists (cluster 3). (I hope
my explanation is clear).
Does anybody know a package or a strategy how to define such clusters?
Thanks and best,
Heike
--
Dr. Heike Pospisil | pospisil at zbh.uni-hamburg.de
University of Hamburg | Center for Bioinformatics
Bundesstrasse 43 | 20146 Hamburg, Germany
phone:+49-40-42838-7303 | fax: +49-40-42838-7312
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