[BioC] Discretization

[Rand, Hugh]

Hi Andrej,

You might try looking at chapter 3 of Alaxander Hartemink's thesis (Principled computational methods for the validation and discovery of genetic regulatory networks), as well as the references therein. His code is in Matlab, but I have a not-very-clean version of it in R.

-Hugh Rand

-----Original Message-----
From: bioconductor-bounces at stat.math.ethz.ch [mailto:bioconductor-bounces at stat.math.ethz.ch] On Behalf Of Steve Lianoglou
Sent: Tuesday, May 13, 2008 1:33 PM
To: Andrej Kastrin
Cc: bioconductor at stat.math.ethz.ch
Subject: Re: [BioC] Discretization

Hi Andrej,

On May 13, 2008, at 4:12 PM, Andrej Kastrin wrote:

> Dear all,
>
> I'm experimenting with machine learning algorithms in microarray
> domain which require discrete feature space. I'm looking for a paper
> or any other type of reference dealing with discretization of
> continuous gene expression data.  If somebody is aware on it, please
> reply to my post.


Here's one that one of my colleagues likes to use:

Quantitative noise analysis for gene expression microarray experiments
http://www.pnas.org/cgi/content/full/99/22/14031

Hope that helps,
-steve

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