[BioC] How to remove some probes from one probeset in the begining?

[pkuonline]

Dear All,

Taking HG-U133_PLUS_2 as an example, one probeset consists of 11 individual probes. I'd like to exclude few non-specific probes from one probeset for genes of interest before the subsequent all analysis. I searched the Archive. It seemed I need to generate a customized CDF file. I am just wondering whether there are some relatively simple methods. If not, could someone show how to modify the pre-existing HG-U133_PLUS_2 CDF file to exclude few probes? 

Many thanks ahead.
 				
Best regards,
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Yong Zhang
Ph.D, Research Scholar
Manyuan Long's Lab
University of Chicago