[BioC] filter gene based on cv

James W. MacDonald jmacdon at med.umich.edu
Thu Jun 19 21:16:08 CEST 2008


Hi Manisha,

 From the help page:

Description:

      'cv' returns a function with values for 'a' and 'b' bound. This
      function takes a single argument. It computes the coefficient of
      variation for the input vector and returns 'TRUE' if the
      coefficient of variation is between 'a' and 'b'. Otherwise it
      returns 'FALSE'

Usage:

      cv(a=1, b=Inf, na.rm=TRUE)

Arguments:

        a: The lower bound for the cv.

        b: The upper bound for the cv.

This seems pretty clear to me - if this is confusing can you tell us 
what part needs fixing?

Best,

Jim


Manisha Brahmachary wrote:
> I am using coefficient of variation as a way of filtering affymetrix data and
> I am new to using this method for filtering data:
> 
>  
> 
> I have a query based on the genefilter package.
> 
>  
> 
> Does this command:
> 
>  
> 
> x <-filterfun(cv(0.5)) mean removing genes that have a coefficient of
> variation of more that 50 %?
> 
>  
> 
> thanks
> 
> 
> 	[[alternative HTML version deleted]]
> 
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-- 
James W. MacDonald, M.S.
Biostatistician
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623



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