[BioC] genefilter (nsFilter function)

James W. MacDonald jmacdon at med.umich.edu
Thu Jun 19 13:22:29 CEST 2008


Hi Anne,

Anne wrote:
> Hi,
>  
> A question about gene filtering:
>  
> I was wondering if anyone could explain me how I should interpret the code
> below.
> I am not sure I understand what it means that IQR(x) > 2.5.  
>   

The IQR is the inter-quartile range, which is the difference between the 
75th and 25th percentile of your data. It is a more robust measure of 
the range of the data, as it will not be affected by a small number of 
extreme values (unlike, say the variance).

Best,

Jim


>  
> iqr <- function(x) IQR(x) > 2.5
> filter <- nsFilter(eset, var.filter=TRUE, var.func = iqr, var.cutoff = 0.5) 
>  
>  
>  
> regards
> Anne
>
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>
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