[BioC] Gene Signature Score Prediction

Sean Davis sdavis2 at mail.nih.gov
Thu Jun 5 12:01:09 CEST 2008


On Wed, Jun 4, 2008 at 9:24 PM, ss <affysnp at gmail.com> wrote:
> Hi list,
>
> I wonder, for gene expression analysis, would it possibe (in the future) ,
> using a bioconductor package,
> that I supply a list of genes of interest with gene expression values and
> fold change (condition 1 vs. condition2)
> and then calculate the scores of this gene signature in each microarray
> sample?

This sounds like class prediction.  There are numerous methods for
doing so in R.  I would recommend looking at the MLInterfaces package
as a starting place, but there are MANY other methods available.
Extensive literature exists on the subject, also.

Sean



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