[BioC] Converting to official gene symbols
James MacDonald
jmacdon at med.umich.edu
Thu Jul 10 16:58:51 CEST 2008
I think the OP wants to map aliases to official gene symbols rather than
mapping affy probe ids to symbols.
Something like this should work:
> library(org.Hs.eg.db)
> eg <- get("GAB", org.Hs.egALIAS2EG)
> symb <- get(eg, org.Hs.egSYMBOL)
> symb
[1] "A1BG"
You can also do these things directly using sql statements if
interested, see the AnnotationDbi vignette for examples.
Best,
Jim
Gundala Viswanath wrote:
> Hi,
>
>
>>> Is there a function available on Bioconductor to convert gene symbol
>>> aliases to official gene symbols?
>
>
> Yes. Is this you what you are looking for?
>
>
>> source('http://bioconductor.org/biocLite.R')
>> biocLite() # installs a number of pacakges
>> biocLite('hgu95av2.db') # a particular chip 'annotation' file
>> library(hgu95av2.db)
>> hgu95av2GENENAME[["1053_at"]]
> [1] "replication factor C (activator 1) 2, 40kDa"
>> hgu95av2SYMBOL[["1053_at"]]
> [1] "RFC2"
>
> Further option can be found here:
>> help(package=hgu95av2.db)
>
> and
>
>> openVignette()
>
>
> - G.V.
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>>
>> --
>> Kang Tu
>>
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--
James W. MacDonald, MS
Biostatistician
UMCCC cDNA and Affymetrix Core
University of Michigan
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