[BioC] 2 conditions time series with different number of sample at each time point

Naomi Altman naomi at stat.psu.edu
Tue Jan 22 18:32:31 CET 2008

Try limma or maanova.


At 11:44 AM 1/22/2008, greg lefebvre wrote:
>Hi all,
>I have received time series dataset which I could not control the
>experimental design.
>And here it is. This is a 2 conditions time series (placebo/treatment) with
>5 time points.
>The main issue I encounter is that the number of replicates at each time
>point is not the same:
>time ttt placebo
>t0 2 7
>t3 3 6
>t7 3 6
>t14 2 5
>t28 5 4
>I tried to use the timecourse package but obviously I can't set the required
>replicate matrix.
>Unless I remove some samples (more or less justified by their poor quality)
>so that the number of sample becomes constant, does anyone could give me
>some good advice ?
>In advance many thanks
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Naomi S. Altman                                814-865-3791 (voice)
Associate Professor
Dept. of Statistics                              814-863-7114 (fax)
Penn State University                         814-865-1348 (Statistics)
University Park, PA 16802-2111

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