[BioC] Senior Bioinformatics Research Scientist Position at Garvan Institute, Australia

[Jean Yee Hwa Yang]

Senior Bioinformatics Research Scientist
http://www.garvan.org.au/pdfs/jobs/Senior%20Bioinformatics%20Research%20Officer%20Dec07.pdf

The Epigenetics Group in the Cancer Program in collaboration with the 
Peter Wills Bioinformatics Centre at the Garvan Institute of Medical 
Research, seek a fulltime Senior Bioinformatics Research Officer to 
perform epigenomic analyses including DNA methylation, chromatin 
modification and micro RNA genome array studies. The major goal will be to 
initiate and develop a range of novel large scale epigenome analyses to 
identify new epigenetic lesions, in particular in breast and prostate 
cancer.

The Garvan Institute is actively engaged in medical research into 
major human diseases involving molecular, cellular, genetic and clinical 
research. The Cancer Research Program is an integrated series of strongly 
interactive Research Groups undertaking research aimed at increasing the 
international knowledge base on the development, progression, treatment 
and prevention of human cancers. The current emphasis of the epigenetic 
laboratory centres on developing a deeper understanding of the mechanism 
responsible for aberrant DNA methylation and chromatin remodelling in 
cancer.

We are seeking an individual with a PhD who has preferably had 
experience in whole genome wide array analyses, in particular ChIP on chip 
tiling arrays. Candidates will have a strong background in 
multi-univariate and Bayesian statistics, and experience in 
machine-learning techniques. Knowledge of the R programming language and 
experience with Gene Set Enrichment Analysis are desirable. The successful 
applicant will also be given freedom and encouragement to further develop 
statistical techniques for data analysis and will be actively involved in 
specific scientific research projects within the Epigenetics group.

The successful applicant will be required to interact closely with phD 
students and postdoctoral scientists to ensure an active and vibrant 
Epigenetic Research Program. The successful applicant will report to the 
head of the Epigenetics group, A/Prof Susan Clark. The position is a 
full-time fixed term appointment for 24 months in the first instance with 
renewal subject to suitability. Written applications including a cover 
letter, Curriculum Vitae, academic transcript and contact details of three 
professional referees, should be forwarded to hr at garvan.org.au, or mailed 
to the address below.

Human Resource Manager Garvan Institute of Medical Research
384 Victoria Street, Darlinghurst, NSW, 2010 Fax: (02) 9295 8151
Email: hr at garvan.org.au
Closing Date for Applications: 30th January 2007