[BioC] Average over probes that share the same clone ID in an expression matrix

[Daniel Brewer]

I have a matrix of expression values with the rows as probeIDs and the
columns as sample names.  I have an associated annotation file with each
row corresponding to the row in the expression matrix.  Some of the
probe IDs share clone IDs.  What I would like to do is for the probes
that share the same clone IDs I would like to find the median and
replace the values in the matrix with the result.

Does anyone know the most efficient way of doing this?

Many thanks
-- 
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Daniel Brewer, Ph.D.
Institute of Cancer Research
United Kingdom
Email: daniel.brewer at icr.ac.uk
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The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP.

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