[BioC] time series analysis

David Ruau David.Ruau at rwth-aachen.de
Thu Mar 1 09:29:56 CET 2007


Hi Ozge,

I would recommend you to have a look at the simpleaffy package from  
Crispin J Miller.
http://bioconductor.org/packages/1.9/bioc/html/simpleaffy.html

The vignette pdf explain how to extract genes significantly regulated  
when you have replicate in you experiment.

David

---
David RUAU
Institute for Biomedical Engineering
-Cell Biology-
Universitatsklinikum Aachen, RWTH
Pauwelsstrasse 30
52074 Aachen
GERMANY

On Feb 28, 2007, at 2:10 PM, Ozge Gursoy-Yuzugulu wrote:

> Hello,
>
> I am working on 2 isogenic cell lines which are treated with a
> certain chemical and 24h, 48h, and 72 hour samples are taken. We now
> have 12 arrays (4x 3 time points) and its duplicate. I searched for
> some methods for the analysis of this kind of data, yet I could not
> find one.
>
> Could you please advise me the most convenient R package and
> statistical method to perform such an analysis...
>
> Thank you all,
>
> Ozge
>



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