[BioC] Error in QAReport function of package affyQCReport

Mark W Kimpel mwkimpel at gmail.com
Sun Jul 29 04:20:13 CEST 2007


Seth and Robert,

Looks like I may have more than one problem. To clarify one point first, 
in my original post I was using affy.batch.sub, which consisted of just 
some of the arrays from my affy.batch. To make sure I'm not having a 
problem with subsetting, in my subsequent posts I am using the affybatch 
object created just today with ReadAffy. No old versions here, just what 
comes out of my sessionInfo().

As you can see below, there may be a problem with my boxplot method but 
also with the affybatch object. The latter is of class AffyBatch but is 
not a valid object.

Thanks, Mark

 > class(affy.batch)
[1] "AffyBatch"
attr(,"package")
[1] "affy"

 > require(affy)
 > showMethods("boxplot")
Error in get(if (inherited) ".AllMTable" else ".MTable", envir = env) :
   variable ".AllMTable" was not found

Enter a frame number, or 0 to exit

1: showMethods("boxplot")
2: .showMethodsTable(getGeneric(f, where = where), includeDefs, 
inherited, cla
3: get(if (inherited) ".AllMTable" else ".MTable", envir = env)


 > validObject(affy.batch)
Error in validObject(affy.batch) :
   invalid class "AffyBatch" object: sampleNames differ between 
assayData and phenoData

Enter a frame number, or 0 to exit

1: validObject(affy.batch)

 > par(mfrow=c(2, 1))
 > ArrayIndex = as.character(1:length(sampleNames(affy.batch)))
 > 
boxplot(affy.batch,names=ArrayIndex,ylab="Log2(Intensity)",xlab="Array 
Index")
Error in attr(groups, "names") <- names :
   'names' attribute [80] must be the same length as the vector [1]

Enter a frame number, or 0 to exit

1: boxplot(affy.batch, names = ArrayIndex, ylab = "Log2(Intensity)", 
xlab = "A
2: boxplot(affy.batch, names = ArrayIndex, ylab = "Log2(Intensity)", 
xlab = "A
3: boxplot.default(affy.batch, names = ArrayIndex, ylab = 
"Log2(Intensity)", x

Selection:

---

Mark W. Kimpel MD  ** Neuroinformatics ** Dept. of Psychiatry
Indiana University School of Medicine

15032 Hunter Court, Westfield, IN  46074

(317) 490-5129 Work, & Mobile & VoiceMail
(317) 663-0513 Home (no voice mail please)

******************************************************************

Robert Gentleman wrote:
> It looks to me like you are using a function named QCReport, not 
> QAReport (and indeed there is no such thing - you might look at 
> affyQAReport, which is in the same package but is very different).
> 
> You can try to see what is happening by looking at the code from 
> signalDist:
> 
> par(mfrow=c(2, 1))
> ArrayIndex = as.character(1:length(sampleNames(object)))
> boxplot(object,names=ArrayIndex,ylab="Log2(Intensity)",xlab="Array Index")
> 
> 
> where instead of object you use affy.batch.sub. The code looks pretty 
> straightforward, so I don't know what the problem might be.  It is a bit 
> odd, it seems to me to use integers in place of the sample names...
> 
> I used the affybatch.example and it worked for me.. ( one issue with 
> that was
> Warning message:
> In data.row.names(row.names, rowsi, i) :
>   some row.names duplicated: 
> 2,26,51,76,101,126,151,176,201,226,251,276,301,326,351,376,401,426,451,476,501,526,551,576,601,626,651,676,701,726,751,776,801,826, 
> 
> ....
> 
> which we may need to look at).
> 
> best wishes
>   Robert
> 
> 
> Mark W Kimpel wrote:
>> I am running into an error when I run QAReport on an affybatch object. 
>> Below is my sessionInfo and output. I am using the devel versions of R 
>> and BioC, all newly updated. Please advise.
>>
>> Thanks,
>> Mark
>>
>> Browse[1]> sessionInfo()
>> R version 2.6.0 Under development (unstable) (2007-06-30 r42095)
>> i686-pc-linux-gnu
>>
>> locale:
>> LC_CTYPE=en_US.UTF-8;LC_NUMERIC=C;LC_TIME=en_US.UTF-8;LC_COLLATE=en_US.UTF-8;LC_MONETARY=en_US.UTF-8;LC_MESSAGES=en_US.UTF-8;LC_PAPER=en_US.UTF-8;LC_NAME=C;LC_ADDRESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=en_US.UTF-8;LC_IDENTIFICATION=C 
>>
>>
>> attached base packages:
>> [1] grDevices datasets  splines   graphics  stats     tools     utils
>> [8] methods   base
>>
>> other attached packages:
>>   [1] hgu95av2cdf_1.17.0     rat2302cdf_1.17.0      affyQCReport_1.15.2
>>   [4] geneplotter_1.15.2     lattice_0.16-2         RColorBrewer_1.0-1
>>   [7] affyPLM_1.13.6         affydata_1.11.2        simpleaffy_2.11.21
>> [10] affycoretools_1.9.2    annaffy_1.9.1          xtable_1.4-6
>> [13] gcrma_2.9.1            matchprobes_1.9.10     biomaRt_1.11.4
>> [16] RCurl_0.8-1            XML_1.9-0              GOstats_2.3.8
>> [19] Category_2.3.16        genefilter_1.15.3      survival_2.32
>> [22] KEGG_1.17.0            RBGL_1.13.3            annotate_1.15.2
>> [25] AnnotationDbi_0.0.83   RSQLite_0.6-0          DBI_0.2-3
>> [28] GO_1.17.0              graph_1.15.10          limma_2.11.9
>> [31] affy_1.15.7            preprocessCore_0.99.12 affyio_1.5.6
>> [34] Biobase_1.15.21
>>
>> loaded via a namespace (and not attached):
>> [1] cluster_1.11.7     grid_2.6.0         KernSmooth_2.22-20
>>
>>  > affy.batch.sub
>> AffyBatch object
>> size of arrays=834x834 features (14 kb)
>> cdf=Rat230_2 (31099 affyids)
>> number of samples=16
>> number of genes=31099
>> annotation=rat2302
>> notes=
>>  > QCReport(affy.batch.sub)
>> Error in attr(groups, "names") <- names :
>>    'names' attribute [16] must be the same length as the vector [1]
>>
>> Enter a frame number, or 0 to exit
>>
>> 1: QCReport(affy.batch.sub)
>> 2: signalDist(object)
>> 3: boxplot(object, names = ArrayIndex, ylab = "Log2(Intensity)", xlab 
>> = "Array
>> 4: boxplot.default(object, names = ArrayIndex, ylab = 
>> "Log2(Intensity)", xlab
>>
>> Selection: 4
>> Called from: eval(expr, envir, enclos)
>> Browse[1]> ls()
>>   [1] "add"        "args"       "at"         "border"     "col"
>>   [6] "groups"     "horizontal" "log"        "n"          "namedargs"
>> [11] "names"      "notch"      "outline"    "pars"       "plot"
>> [16] "range"      "*tmp*"      "varwidth"   "width"      "x"
>> Browse[1]> names
>>   [1] "1"  "2"  "3"  "4"  "5"  "6"  "7"  "8"  "9"  "10" "11" "12" "13" 
>> "14" "15"
>> [16] "16"
>> Browse[1]> names(group)
>> NULL
>> Browse[1]> names(groups)
>> [1] ""
>> Browse[1]> names(groups) <- names
>> Error during wrapup: 'names' attribute [16] must be the same length as 
>> the vector [1]
>> Browse[1]>
>



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