[BioC] Affystart function in Affycoretools

James W. MacDonald jmacdon at med.umich.edu
Tue Jul 24 15:44:53 CEST 2007


Hi Sachin,

I fixed the problem and pushed to the release repository. The patched 
version of affycoretools will be 1.8.1, and should appear in the next 
few days.

Thanks for the bug report.

Best,

Jim



Sachin Mathur wrote:
> Dear Jim,
> 
> I finally managed to get our IT to sort out the firewall issue and
> update the packages as you had indicated, but I still get the same
> error.
> 
>> expset = affystart(fnames,plot=FALSE,pca=FALSE,express = c("mas5"))
> background correction: mas
> PM/MM correction : mas
> expression values: mas
> background correcting...done.
> 31099 ids to be processed
> |                    |
> |####################|
> Getting probe level data...
> Computing p-values
> Making P/M/A Calls
> Error in function (classes, fdef, mtable)  :
>         unable to find an inherited method for function "se.exprs", for
> signature "ExpressionSet"
> In addition: Warning messages:
> 1: The phenoData class is deprecated, use AnnotatedDataFrame (with
> ExpressionSet) instead
> 2: Incompatible phenoData object. Created a new one.
>  in: read.affybatch(filenames = filenames, phenoData = phenoData)
> Execution halted
> 
>> sessionInfo()
> R version 2.5.0 (2007-04-23)
> x86_64-unknown-linux-gnu
> 
> locale:
> LC_CTYPE=en_US.UTF-8;LC_NUMERIC=C;LC_TIME=en_US.UTF-8;LC_COLLATE=en_US.UTF-8;LC_MONETARY=en_US.UTF-8;LC_MESSAGES=en_US.UTF-8;LC_PAPER=en_US.UTF-8;LC_NAME=C;LC_ADDRESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=en_US.UTF-8;LC_IDENTIFICATION=C
> 
> attached base packages:
> [1] "splines"   "tools"     "stats"     "graphics"  "grDevices"
> "utils"
> [7] "datasets"  "methods"   "base"
> 
> other attached packages:
>    rat2302cdf affycoretools       annaffy        xtable         gcrma
>      "1.16.0"       "1.8.0"       "1.8.1"       "1.4-6"       "2.8.1"
>   matchprobes       biomaRt         RCurl           XML       GOstats
>       "1.8.1"      "1.10.1"       "0.8-0"       "1.7-1"       "2.2.6"
>      Category        Matrix       lattice    genefilter      survival
>       "2.2.3"  "0.999375-0"      "0.16-2"      "1.14.1"        "2.32"
>          KEGG          RBGL      annotate            GO         graph
>      "1.16.1"      "1.12.0"      "1.14.1"      "1.16.0"      "1.14.2"
>         limma          affy        affyio       Biobase
>      "2.10.5"      "1.14.2"       "1.4.1"      "1.14.1"
> 
> While updating the packages, I got some warnings w.r.t. the Matrix
> package, but did not get any error messages.
> 
> Regards,
> Sachin
> 
> 
>>>> "James W. MacDonald" <jmacdon at med.umich.edu> 7/5/2007 4:14 PM >>>
> Hi Sachin,
> 
> Sachin Mathur wrote:
>> Dear Users,
>>
>> I have recently upgraded the bioconductor package to 2.0  from 1.9.
> The
>> affystart function in affycoretools used to work just fine with bioc
> 1.9
>> but I get the following errors on 2.0. 
>>
>>> fnames = c("LKM1_051407.CEL","LKM2_051407.CEL")
>>> expset = affystart(fnames,plot=FALSE,pca=FALSE,express = c("mas5"))
>> background correction: mas
>> PM/MM correction : mas
>> expression values: mas
>> background correcting...done.
>> 45101 ids to be processed
>> |                    |
>> |####################|
>> Getting probe level data...
>> Computing p-values
>> Making P/M/A Calls
>> Error in function (classes, fdef, mtable)  :
>>         unable to find an inherited method for function "se.exprs",
> for
>> signature "ExpressionSet"
>> In addition: Warning messages:
>> 1: The phenoData class is deprecated, use AnnotatedDataFrame (with
>> ExpressionSet) instead
>> 2: Incompatible phenoData object. Created a new one.
>>  in: read.affybatch(filenames = filenames, phenoData = phenoData)
>> Execution halted
>>
>>
>> I tried to look for se.exprs, but couldn't make any headway. Here's
> the
>> output from sessionInfo()
>>
>>> sessionInfo()
>> R version 2.5.0 (2007-04-23)
>> x86_64-unknown-linux-gnu
>>
>> locale:
>>
> LC_CTYPE=en_US.UTF-8;LC_NUMERIC=C;LC_TIME=en_US.UTF-8;LC_COLLATE=en_US.UTF-8;LC_MONETARY=en_US.UTF-8;LC_MESSAGES=en_US.UTF-8;LC_PAPER=en_US.UTF-8;LC_NAME=C;LC_ADDRESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=en_US.UTF-8;LC_IDENTIFICATION=C
>> attached base packages:
>> [1] "splines"   "tools"     "stats"     "graphics"  "grDevices"
>> "utils"
>> [7] "datasets"  "methods"   "base"
>>
>> other attached packages:
>>     mouse4302  mouse4302cdf affycoretools       annaffy       
> xtable
>>      "1.16.0"      "1.16.0"       "1.8.0"       "1.8.1"      
> "1.4-6"
>>         gcrma   matchprobes       biomaRt         RCurl          
> XML
>>       "2.8.1"       "1.8.1"      "1.10.0"       "0.8-0"      
> "1.7-1"
>>         limma          affy        affyio       GOstats     
> Category
>>      "2.10.5"      "1.14.1"       "1.4.0"       "2.2.6"      
> "2.2.3"
>>        Matrix       lattice    genefilter      survival         
> KEGG
>>   "0.99875-2"      "0.15-4"      "1.14.1"        "2.31"     
> "1.16.1"
>>          RBGL      annotate       Biobase            GO        
> graph
>>      "1.12.0"      "1.14.1"      "1.14.0"      "1.16.0"     
> "1.14.2"
> 
> Looks like mismatched versions. Both affy and affycoretools are old. I
> 
> would update:
> 
> biocLite("Biobase")
> library(Biobase)
> repos <- biocReposList()
> update.packages(repos=repos, ask=FALSE)
> 
> Best,
> 
> Jim
> 
> 
>> Thanks for the help,
>>
>> Sachin Mathur
>> 2027 Kansas Life Sciences Innovations Center
>> 3901 Rainbow Blvd. 
>> Kansas City, KS 66160-7401 
>> Phone: (913) 588-5966 
>> Fax: (913) 588-5677 
>> smathur at kumc.edu 
>>
>> _______________________________________________
>> Bioconductor mailing list
>> Bioconductor at stat.math.ethz.ch 
>> https://stat.ethz.ch/mailman/listinfo/bioconductor 
>> Search the archives:
> http://news.gmane.org/gmane.science.biology.informatics.conductor 
> 
> 

-- 
James W. MacDonald, M.S.
Biostatistician
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623



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