[BioC] GO terms not found in goTools and GO
Lina Hultin-Rosenberg
lina.hultin-rosenberg at ki.se
Fri Jul 20 21:17:21 CEST 2007
Thank you so much for the information! I did not now exactly how the
different packages worked, now I know and understand better the problems
I ran into. I use biomart ensembl for the GO queries.
Best regards,
Lina
Seth Falcon skrev:
> Wolfgang Huber <huber at ebi.ac.uk> writes:
>
>> Dear Lena,
>>
>> the point to realize is that biomaRt queries an online database (you
>> didn't tell us which one you use), while the GO package is assembled and
>> packaged by friendly curators in Seattle every couple of months.
>>
>> According to this site
>> http://www.ebi.ac.uk/ego/DisplayGoTerm?id=GO:0060070
>> your term was last modified 2007-03-16, which could explain why it is
>> not yet in the latest GO package (version 1.17.0).
>>
>> If you want an consistent set of GO terms throughout, please use the
>> humanLLmappings (soon to be humanEGmappings) package for gene-GO
>> associations, not biomaRt. If you use biomaRt, you need to spend more
>> effort dealing with the dynamic nature of genome annotation (this is not
>> our fault, this is the state of the science).
>
> Good advice. I want to clarify one detail:
>
> We are working on new Entrez Gene based organism specific annotation
> packages for human, mouse and rat. They are intended as New And
> Improved versions of <organism>LLMappings. We have not finalized how
> we will name them, and almost surely they will not be humanEGmappings.
> I will start a thread on bioc-devel today with some proposed naming
> schemas for those that are interested.
>
> Best,
>
> + seth
>
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