[BioC] R.fold values from sam and siggenes

Ettinger, Nicholas nicholas-ettinger at uiowa.edu
Fri Mar 3 18:28:16 CET 2006


Hello Dr. Schwender!

Quick question for you...I couldn't seem to find an answer to this in
the 'siggenes' vignette.

Are the R-fold values that are calculated in log scale or not?  I.e. if
I have an R-fold value of 1.2 does that mean that the treated samples
are 1.2x higher than the untreated or that the treated samples are 2^1.2
times higher?  Similarly, does an R-fold of 0.8 mean untreated is 0.8 of
treated expression levels or 2^0.8 of treated?

Thank you for the clarification.
---Nick



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