[BioC] multi PMT scan combination
schmatthew at gmail.com
Thu Jun 15 16:26:24 CEST 2006
If I understand you correctly, you wish to merge datasets obtained
from doing multiple scans of the same set of slides. The best
treatment I've read about this was in:
Piepho et al. (2006) Combining signals from spotted cDNA microarrays
obtained at different scanning intensities. Bioinformatics (January
17, I think).
Their approach is implemented in SAS and they will email you the code.
If I recall correctly, the code is written for seven (!) repeat scans
and not less. Unfortunately, I don't think it's available in R, and
I'm nowhere near the programmer/mathematician who could do it.
Nonetheless, the paper is worth reading. If someone else has better
information, I'd like to hear about it too.
Has anyone set up scripts to combine multi PMT readings (multiple gpr files
for the same slide)?
Help and information would be highly appreciated,
Senior Research Specialist
Department of Plant Sciences
University of Arizona
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