[BioC] affycoretools limma2annaffy fold change output question
James W. MacDonald
jmacdon at med.umich.edu
Wed Apr 19 17:03:52 CEST 2006
Hi Mark,
Kimpel, Mark William wrote:
> In the package affycoretools, how does the function limma2annaffy
> determine which fold change to output in the case of multiple contrasts?
> In topTable, one can specify the coefficient, but I don't see that this
> is the case with limma2annaffy.
In limma2annaffy, one of the arguments you supply is the contrasts
matrix. This is used to extract the fold change, t-statistic, p-value,
and expression values for the resulting HTML or text table.
The default is to output results for _all_ contrasts, so you don't
explicitly specify the coefficient.
HTH,
Jim
>
>
> Thanks,
>
> Mark W Kimpel
> Indiana University School of Medicine
>
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--
James W. MacDonald, M.S.
Biostatistician
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623
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