[BioC] paired t test for siblings?
Naomi Altman
naomi at stat.psu.edu
Mon Nov 7 21:17:54 CET 2005
I would use Limma, with sib pairs as a block. This has all the
advantages of a paired t-test with better power.
At 12:53 PM 11/7/2005, Li,Qinghong,ST.LOUIS,Molecular Biology wrote:
>Hi BioC,
>
>I have a data set from an experiemnt that has a control and a
>treatment group for a total of 8 dogs. Each group has 4 bioloigical
>replicates (4 dogs). Animals are in pairs in terms of siblings. Is
>paired test appropriate in this case?
>
>Due to low replicate number (4), is traditional t test appropriate?
>If not, what would be other options in BioC packages besides SAM?
>
>Thanks in advance!
>Johnny
>
>
> [[alternative HTML version deleted]]
>
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Naomi S. Altman 814-865-3791 (voice)
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Dept. of Statistics 814-863-7114 (fax)
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