[BioC] Generic Loess Normalization

[Wolfgang Huber]

Hi Gene,

for general local regression, you may also want to look at the locfit 
package (on CRAN) which one might call a faster and more advanced 
version of loess. It provides better diagnostic output and there is a 
very nice textbook going with it.

  Best wishes
   Wolfgang

James W. MacDonald wrote:
> Gene Cutler wrote:
> 
>> Of the various Bioconductor methods, is there any which performs a 
>> fairly generic loess normalization, leaving out fancy stuff like 
>> print-tip normalization, etc?
>>
>> I'd like to write some code based on this, so I'd like to see a 
>> stripped-down example if there is one out there.
> 
> 
> You might look at loessFit in the limma package. Much of the heavy 
> lifting appears to be done in C, however.
> 
> Jim
> 

-------------------------------------
Wolfgang Huber
European Bioinformatics Institute
European Molecular Biology Laboratory
Cambridge CB10 1SD
England
Phone: +44 1223 494642
Fax:   +44 1223 494486
Http:  www.ebi.ac.uk/huber