[BioC] GOLOCUSID and GOALLLOCUSID disagree with AmiGO
Dick Beyer
dbeyer at u.washington.edu
Fri Jan 28 22:33:36 CET 2005
I am having some trouble understanding the correct usage of GOLOCUSID and GOALLLOCUSID. I can't get the list of LocusLink identifiers output for a particular GOID to agree with AmiGO. Also, for this particular GOID, GO:0000158, the return from GOLOCUSID and GOALLLOCUSID are the same, which seems wrong. I am using the latest development version of GO.
Then again, perhaps I am not approaching this correctly as I have not used these functions before.
AmiGO shows 8 genes for GO:0000158, and both GOLOCUSID and GOALLLOCUSID show 33.
Would someone please look at the following code example and tell me what I am doing wrong?
>require("GO") || stop("GO unavailable")
>myGOALLLOCUSID <- as.list(GOALLLOCUSID)
>allGOALLLOCUSID <- names(myGOALLLOCUSID)
>allGOALLLOCUSID <- sub("GO:","",allGOALLLOCUSID)
>myGOLOCUSID <- as.list(GOLOCUSID)
>allGOLOCUSID <- names(myGOLOCUSID)
>allGOLOCUSID <- sub("GO:","",allGOLOCUSID)
>which(allGOLOCUSID == "0000158")
[1] 3370
> myGOLOCUSID[3370]
$"GO:0000158"
IDA IDA IEA IEA IEA IEA IEA IEA IEA IEA IEA IEA IEA
24673 5520 116663 19053 24666 24668 24669 24672 24673 24674 24675 25594 65179
IMP ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS
45959 117281 19045 19046 19052 19053 19055 28227 319520 39337 45959 47877 63953
ISS NAS NR NR TAS TAS TAS
67857 45959 5518 5519 19052 24672 5516
>which(allGOALLLOCUSID == "0000158")
[1] 2856
> myGOALLLOCUSID[2856]
$"GO:0000158"
IDA IDA IEA IEA IEA IEA IEA IEA IEA IEA IEA IEA IEA
24673 5520 116663 19053 24666 24668 24669 24672 24673 24674 24675 25594 65179
IMP ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS ISS
45959 117281 19045 19046 19052 19053 19055 28227 319520 39337 45959 47877 63953
ISS NAS NR NR TAS TAS TAS
67857 45959 5518 5519 19052 24672 5516
AmiGO tells me GO:0000158 has the genes:
19045 Ppp1ca
19046 Ppp1cb
19052 Ppp2ca
19053 Ppp2cb
19055 Ppp3ca
63953 Dusp10
319520 Dusp4
67857 Ppp6c
base 2.0.1
datasets 2.0.1
utils 2.0.1
grDevices 2.0.1
graphics 2.0.1
stats 2.0.1
methods 2.0.1
tools 2.0.1
Biobase 1.5.0
reposTools 1.5.1
affy 1.5.8
matchprobes 1.0.12
gcrma 1.1.1
qvalue 1.1
siggenes 1.2.11
limma 1.8.6
GO 1.6.8
xtable 1.2-4
Thanks very much for any help or suggestions,
Dick
*******************************************************************************
Richard P. Beyer, Ph.D. University of Washington
Tel.:(206) 616 7378 Env. & Occ. Health Sci. , Box 354695
Fax: (206) 685 4696 4225 Roosevelt Way NE, # 100
Seattle, WA 98105-6099
http://depts.washington.edu/ceeh/ServiceCores/FC5/FC5.html
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