[BioC] genes variances
Robert Gentleman
rgentlem at fhcrc.org
Fri Apr 22 16:44:47 CEST 2005
Hmm, google will do most of that work for you, Wolfgang Huber has done
a lot of work on this (see the package vsn, which contains code for
carrying out such an analysis).
On Apr 22, 2005, at 5:12 AM, E Motakis, Mathematics wrote:
> Dear all,
>
> Recently, I have been working on variance stabilization techniques for
> cDNA microarrays. I have been studying the papers:
>
> I. Rocke and Durbin, (2001), `A model for measurement error for gene
> expression arrays', J. Comput. Biol, 8, 557--569 and
>
> II. Durbin, Hardin, Hawkins, and Rocke, (2002), `A
> variance-stabilizing transformation for gene-expression microarray
> data', Bioinformatics, 18, S105-S110.
>
> Their variance stabilization seems to work well for most of the genes
> I replicate (and for my data). I wonder if someone is aware of other
> related papers to that subject (not only by those authors). Is there
> any other technique for variance stabilization available in the
> microarrays literature?
>
> Thank you in advance.
>
> Makis Motakis
>
> ----------------------
> E Motakis, Mathematics
> E.Motakis at bristol.ac.uk
>
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>
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