[BioC] Adaptive background correction error
a.e.schiel at lumc.nl
Mon Apr 4 12:10:48 CEST 2005
I tried to use the adaptive background correction for a set of 22 arrays
(2 colour). For array no 17 I get the following error
RGb<-backgroundCorrect(RG, method="normexp", offset=50)
Error in fit.normexp(foreground = RG$R[, j], background = RG$Rb[, j]) :
optim failure: degeneracy of the Nelder-Mead simplex
There is nothing obviously wrong with that array so is it the array
that's causing the problem or something else?
And what is the Nelder-Mead simplex????
I am running R 2.0.1 + Bioconductor under Debian testing and limma
Anja E. Schiel, Ph.D.
Departments of General Internal Medicine and Human Genetics
Leiden University Medical Center
PO Box 9503
2300 RA Leiden
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