[BioC] multtest data preprocessing questions
ulask at bu.edu
Mon May 24 20:36:22 CEST 2004
i am trying to use multest R package(source package) and i am puzzled
by the following:
1-What kind of initial processing is done to the data?
I thought you get the golub.RData under the /multtest/data directory by
running golub.R script that is attached(in the inst/doc directory) but
when I run that script on the original data, and do "golub[1:4, 1:4]" i
cannot get the same thing as in the documentation, i get:
Gene.Accession.Number call call.1 call.2
36 2.000000 2.000000 2.017033 2.000000
37 2.332438 2.064458 2.677607 2.190332
38 2.901458 2.636488 3.168497 2.618048
39 4.162505 2.788875 3.753506 3.685742
2- My other question is, why is the need to center, and to scale the
data in the golub.R script, is it ever used?
3-Also in the same script, the class labels are initialized to 1, and
) although all the statistical tests upstream require 0, or 1 as
labels. Am I wrong?
Is anyone running into similar problems.
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