[BioC] How to filter up- and down-regulated genes?

Sean Davis sdavis2 at mail.nih.gov
Thu May 20 13:19:13 CEST 2004

Assuming you were using a t-test, you could look at the sign (positive or
negative) of the test from the multtest procedure.  You could also look at
the expression values themselves (very useful, as there are many instances
where statistical significance may not be at all biologically interesting,
and vice-versa).  


On 5/20/04 7:13, "Vitalina Komashko" <vmkomashko at bionet.nsc.ru> wrote:

> Hello!
> I analize Affymetrix chips. There are two groups of transgenic and
> nontransgenic mice with 3 samples in each group. I normalised my data using
> rma, and calculated an adjusted p-value using multtest package. I have found
> out that there are about 64 differentially expressed genes between these two
> groups (alpha=0.01) (I used Bonferroni procedure).
> Next question is which of these genes are up- and down-regulated? How could I
> find out it?
> Thank you very much!
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