[BioC] median polish vs mas

Naomi Altman naomi at stat.psu.edu
Mon May 17 16:15:17 CEST 2004

I have been wondering why the default in justRMA is 
summary.method="medianpolish"  instead of "mas" which is Tukey's 
biweight.  Since we are already doing quantile normalization, doesn't the 
extra between array step imposed by median polish give the possibility of 
masking differential expression?

Naomi S. Altman                                814-865-3791 (voice)
Associate Professor
Bioinformatics Consulting Center
Dept. of Statistics                              814-863-7114 (fax)
Penn State University                         814-865-1348 (Statistics)
University Park, PA 16802-2111

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