[BioC] Limma:short question

Gordon K Smyth smyth at wehi.EDU.AU
Thu Jan 29 02:00:46 MET 2004


> Hi all,
>
> I am using limma on Affymetrix data and want to fit a linear model with
>
> fit <- lm.series(exprs(E), design)
>
> My question is:
> Is the data in E supposed to be on a log scale (like after using vsn) or
> not?

Yes.

Gordon

> Thanks for your help,
> Julia
>
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