[BioC] iterative gcrma on 92 slides?

Rafael A. Irizarry ririzarr at jhsph.edu
Wed Jan 28 19:51:32 MET 2004


the batches is a better idea.

writing justGCRMA is not that hard. if anybody wants to try
please contact me.

-r


On Wed, 28 Jan 2004, Dick Beyer wrote:

> I would like to do gcrma on 92 chips, type mgu74av2.  I know I won't be able to if I just send all 92 to gcrma.  
> 
> I was wondering if there were a way to iteratively get to the answer.  Would it be useful to do gcrma in doable batches, say 20 or so, then do quantile normalization on all 92?
> 
> Or can I do justRMA on the 92, then somehow process the exprSet to achieve a gcrma result?
> 
> I am willing to try different approaches, but I am hoping for some advice on which ways might be best.
> 
> Thanks very much,
> Dick
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> Richard P. Beyer, Ph.D.	University of Washington
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