[BioC] RNA degradation plots

Harry Hurd hhurd1 at nc.rr.com
Thu Jan 8 23:45:05 MET 2004


Hello,

We are looking at some HG-U133A arrays in which the RNA degredation plot shows a large increase from 5' to 3'. Is it neccessarily bad? Is there a condition on the slope that defines "bad"?

Here are the slopes and pvs.

slope 1.88 1.34 1.86 1.71
pvalue 1.94e-07 3.74e-05 1.14e-07 6.48e-07

Any advice, or pointers to references would be appreciated.

Harry Hurd

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