[BioC] Linear and spline normalization

[Stephen Nyangoma]

Hi all,
I am reading through a paper by 

Shadt, Li, Su & Wong: Analyzing High- Density Oligonucleotide Gene
Expression Array Data. Journal of Cellular Biochemistry 80:192-202.

They discuss linear and spline normalizations. Have these methods been
implemented in Bioconductor? or has anyone codes implementing especially
the splines method?

Regards. Stephen.