[BioC] Bioconductor
Robert Cribbie
cribbie at criblab.yorku.ca
Wed Nov 12 20:13:50 MET 2003
I am a "newcomer" to the field of microarray analysis and I have run into
a snag trying to analyze some cdna data.
To determine if the same gene in two different groups is differentially
expressed I assume that I am comparing the expression levels of the two
groups after normalization. However, when I use bioconductor to normalize
the data (e.g., maNorm) I only end up with matrices of log ratios
(maM). How do I compare the expression levels of the two groups if I only
have the log ratios (and not the normalized expression levels).
Thanks for any help that you can provide.
Rob.
****************************************************************************
Robert A. Cribbie
Assistant Professor Associate Coordinator
Department of Psychology Statistical Consulting Service
York University Institute for Social Research
Toronto, Ontario, Canada York University
M3J 1P3
Phone: 416-736-5115 (x88615) E-Mail: cribbie at yorku.ca
Fax: 416-736-5814 Website: http://www.psych.yorku.ca/cribbie
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