[BioC] Testing for significant genes with RMA

Naomi Altman naomi at stat.psu.edu
Fri Dec 19 16:20:59 MET 2003


Eric,
If I understand your question, it doesn't matter.  (y-m)-(x-m)=y-x.

--Naomi

At 10:00 AM 12/19/2003, Eric wrote:
>Hi,
>
>Which would be more appropriate to use as the initial data for a 'per gene
>parametric test', the output of justRMA or the output of justRMA normalized
>to the mean of a control group (log of fold change)?
>
>
>Eric Blalock, PhD
>Dept Pharmacology, UKMC
>859 323-8033
>
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Naomi S. Altman                                814-865-3791 (voice)
Associate Professor
Bioinformatics Consulting Center
Dept. of Statistics                              814-863-7114 (fax)
Penn State University                         814-865-1348 (Statistics)
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