[Bioc-devel] New annotation hub package?

Sara López Ruiz de Vargas |opez_@ @end|ng |rom mo|gen@mpg@de
Wed Apr 24 15:17:52 CEST 2024


Dear developers community,

We are currently developing a package for which we are quite sure we 
will need a supporting AnnotationHub or ExperimentHub package to go with 
it.
We are using a set of gene annotations (GENCODE version 40 hg38) and 
enhancer annotations (ENCODE registry of cCREs v3), which are not 
available in the AnnotationHub.
Correct me if I’m wrong.

On top of that, our package depends on in house precomputed datasets 
that occupy a lot of space.
We have solved this issue temporarily by making the annotations and the 
precomputed data into RSQLite databases which the user can download 
(into inst/extada)
once the package is installed. This however makes the inst/extdata 
folder really large (above 5GB). Most likely a Hub package would be a 
better solution.

When looking at the documentation ( 
https://bioconductor.org/packages/devel/bioc/vignettes/HubPub/inst/doc/CreateAHubPackage.html 
) one of the first things
mentioned is to contact a Bioconductor team member. I was wondering if I 
could find someone in this forum who could help with this.

Best regards,

Sara Lopez

-- 
Sara López Ruiz de Vargas
Max Planck Institute for Molecular Genetics
Vingron Lab / Dept. of Computational Molecular Biology
Ihnestraße 63-⁠73
14195 Berlin
GERMANY



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