[Bioc-devel] Query about hgu133plus2 database

[Obenchain, Valerie]

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Valerie

On 12/05/2016 01:15 PM, Bhattacharya, A (onco) wrote:
> Hi,
>
> I was trying to get the gene mapping for one of the datasets in Affymetrix. I found a dissimilarity between Affymetrix file and the database in hgu133plus2.
>
> As per example, For the probeset "1553011_at", I have found a mapping to both these ENTREZ ID's 6872 /// 138474 in the file downloaded from AFfymetrix website. But in the hgu133plus2 database it is only mapped to 138474. Moreover, in all the cases where a probeset is mapped to multiple genes in the Affymetrix file, only one of them is chosen as mapped gene in the hgu133plus2. I wish to know in what basis the other genes are ommitted from mapping. Was there any algorithm to select the mapped gene among the multiple one's?
>
> The link to the Affymetrix file:- http://www.affymetrix.com/Auth/analysis/downloads/na36/ivt/HG-U133_Plus_2.na36.annot.csv.zip
>
> Regards,
>
> Arkajyoti Bhattacharya
>
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