[Bioc-devel] Cannot interact with a BigWig file on the web with rtracklayer (Windows specific)

Leonardo Collado Torres lcollado at jhu.edu
Tue Sep 30 17:00:53 CEST 2014


Hello,

I ran into an issue interacting with BigWig files over the network
with `rtracklayer`. For some reason, the issue is Windows-specific and
I don't understand why.

Basically, I run the short code at
https://gist.github.com/lcolladotor/0ab8ab3d904d21110637 It works on a
Mac, but it fails on Windows. The same is true for using
rtracklayer::import().

Any help will be greatly appreciated.

Thanks,
Leonardo


####### Windows info ###########

> suppressPackageStartupMessages(library('rtracklayer'))
>
> ## Attempt with 1 file
> bw <- BigWigFile('http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB97.AMY.bw')
> seql <- seqlengths(bw)
Warning message:
In seqinfo(x) : Invalid argument
Can't open http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB97.AMY.bw
to read
Error in seqlengths(seqinfo(x)) :
  error in evaluating the argument 'x' in selecting a method for
function 'seqlengths': Error in seqinfo(x) : UCSC library operation
failed
> traceback()
3: seqlengths(seqinfo(x))
2: seqlengths(bw)
1: seqlengths(bw)
>
> ## Then another file
> bw2 <- BigWigFile('http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB114.A1C.bw')
> seql2 <- seqlengths(bw2)
Warning message:
In seqinfo(x) : Invalid argument
Can't open http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB114.A1C.bw
to read
Error in seqlengths(seqinfo(x)) :
  error in evaluating the argument 'x' in selecting a method for
function 'seqlengths': Error in seqinfo(x) : UCSC library operation
failed
>
> ## Check
> identical(seql, seql2)
Error in identical(seql, seql2) : object 'seql' not found
>
> ## Session info
> devtools::session_info()
Session info------------------------------------------------------------------------------------------------------------
 setting  value
 version  R version 3.1.1 (2014-07-10)
 system   x86_64, mingw32
 ui       Rgui
 language (EN)
 collate  English_United States.1252
 tz       America/New_York

Packages----------------------------------------------------------------------------------------------------------------
 package           * version  date       source
 base64enc           0.1.2    2014-06-26 CRAN (R 3.1.1)
 BatchJobs           1.4      2014-09-24 CRAN (R 3.1.1)
 BBmisc              1.7      2014-06-21 CRAN (R 3.1.1)
 BiocGenerics      * 0.11.5   2014-09-13 Bioconductor
 BiocParallel        0.99.22  2014-09-23 Bioconductor
 Biostrings          2.33.14  2014-09-07 Bioconductor
 bitops              1.0.6    2013-08-17 CRAN (R 3.1.0)
 brew                1.0.6    2011-04-13 CRAN (R 3.1.0)
 checkmate           1.4      2014-09-03 CRAN (R 3.1.1)
 codetools           0.2.9    2014-08-21 CRAN (R 3.1.1)
 DBI                 0.3.1    2014-09-24 CRAN (R 3.1.1)
 devtools            1.6      2014-09-23 CRAN (R 3.1.1)
 digest              0.6.4    2013-12-03 CRAN (R 3.1.0)
 fail                1.2      2013-09-19 CRAN (R 3.1.0)
 foreach             1.4.2    2014-04-11 CRAN (R 3.1.0)
 futile.logger       1.3.7    2014-01-23 CRAN (R 3.1.1)
 futile.options      1.0.0    2010-04-06 CRAN (R 3.1.1)
 GenomeInfoDb      * 1.1.23   2014-09-28 Bioconductor
 GenomicAlignments   1.1.30   2014-09-23 Bioconductor
 GenomicRanges     * 1.17.42  2014-09-23 Bioconductor
 IRanges           * 1.99.28  2014-09-10 Bioconductor
 iterators           1.0.7    2014-04-11 CRAN (R 3.1.0)
 lambda.r            1.1.6    2014-01-23 CRAN (R 3.1.1)
 RCurl               1.95.4.3 2014-07-29 CRAN (R 3.1.1)
 Rsamtools           1.17.34  2014-09-20 Bioconductor
 RSQLite             0.11.4   2013-05-26 CRAN (R 3.1.0)
 rstudioapi          0.1      2014-03-27 CRAN (R 3.1.1)
 rtracklayer       * 1.25.16  2014-09-10 Bioconductor
 S4Vectors         * 0.2.4    2014-09-14 Bioconductor
 sendmailR           1.2.1    2014-09-21 CRAN (R 3.1.1)
 stringr             0.6.2    2012-12-06 CRAN (R 3.1.0)
 XML                 3.98.1.1 2013-06-20 CRAN (R 3.1.0)
 XVector             0.5.8    2014-09-07 Bioconductor
 zlibbioc            1.11.1   2014-05-09 Bioconductor
>







########## Mac info ############





> suppressPackageStartupMessages(library('rtracklayer'))
>
> ## Attempt with 1 file
> bw <- BigWigFile('http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB97.AMY.bw')
> seql <- seqlengths(bw)
>
> ## Then another file
> bw2 <- BigWigFile('http://download.alleninstitute.org/brainspan/MRF_BigWig_Gencode_v10/bigwig/HSB114.A1C.bw')
> seql2 <- seqlengths(bw2)
>
> ## Check
> identical(seql, seql2)
[1] TRUE
>
> ## Session info
> devtools::session_info()
Session info------------------------------------------------------------------------------------------------------------------------
 setting  value
 version  R version 3.1.1 (2014-07-10)
 system   x86_64, darwin10.8.0
 ui       AQUA
 language (EN)
 collate  en_US.UTF-8
 tz       America/New_York

Packages----------------------------------------------------------------------------------------------------------------------------
 package           * version  date       source
 base64enc           0.1.2    2014-06-26 CRAN (R 3.1.0)
 BatchJobs           1.4      2014-09-24 CRAN (R 3.1.1)
 BBmisc              1.7      2014-06-21 CRAN (R 3.1.0)
 BiocGenerics      * 0.11.5   2014-09-13 Bioconductor
 BiocParallel        0.99.22  2014-09-24 Bioconductor
 Biostrings          2.33.14  2014-09-09 Bioconductor
 bitops              1.0.6    2013-08-17 CRAN (R 3.1.0)
 brew                1.0.6    2011-04-13 CRAN (R 3.1.0)
 checkmate           1.4      2014-09-03 CRAN (R 3.1.1)
 codetools           0.2.9    2014-08-21 CRAN (R 3.1.1)
 DBI                 0.3.1    2014-09-24 CRAN (R 3.1.1)
 devtools            1.6      2014-09-23 CRAN (R 3.1.1)
 digest              0.6.4    2013-12-03 CRAN (R 3.1.0)
 fail                1.2      2013-09-19 CRAN (R 3.1.0)
 foreach             1.4.2    2014-04-11 CRAN (R 3.1.0)
 futile.logger       1.3.7    2014-01-23 CRAN (R 3.1.0)
 futile.options      1.0.0    2010-04-06 CRAN (R 3.1.0)
 GenomeInfoDb      * 1.1.23   2014-09-28 Bioconductor
 GenomicAlignments   1.1.30   2014-09-23 Bioconductor
 GenomicRanges     * 1.17.42  2014-09-23 Bioconductor
 IRanges           * 1.99.28  2014-09-10 Bioconductor
 iterators           1.0.7    2014-04-11 CRAN (R 3.1.0)
 lambda.r            1.1.6    2014-01-23 CRAN (R 3.1.0)
 RCurl               1.95.4.3 2014-07-29 CRAN (R 3.1.1)
 Rsamtools           1.17.34  2014-09-20 Bioconductor
 RSQLite             0.11.4   2013-05-26 CRAN (R 3.1.0)
 rstudioapi          0.1      2014-03-27 CRAN (R 3.1.0)
 rtracklayer       * 1.25.16  2014-09-10 Bioconductor
 S4Vectors         * 0.2.4    2014-09-14 Bioconductor
 sendmailR           1.2.1    2014-09-21 CRAN (R 3.1.1)
 stringr             0.6.2    2012-12-06 CRAN (R 3.1.0)
 XML                 3.98.1.1 2013-06-20 CRAN (R 3.1.0)
 XVector             0.5.8    2014-09-07 Bioconductor
 zlibbioc            1.11.1   2014-04-19 Bioconductor
>





Leonardo Collado Torres, PhD Candidate
Department of Biostatistics
Johns Hopkins University
Bloomberg School of Public Health
Website: http://www.biostat.jhsph.edu/~lcollado/
Blog: http://lcolladotor.github.io/



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