[Bioc-devel] New package: PAA
michael.turewicz at rub.de
Tue Oct 14 06:39:42 CEST 2014
I would like to introduce a new package to you: PAA.
PAA (Protein Array Analyzer) is a package for protein microarray data
analysis (esp., ProtoArray data). PAA imports single color protein
microarray data that has been saved in gpr file format. After pre-processing
(background correction, batch filtering, normalization) univariate feature
pre-selection is performed (e.g., using the "minimum M statistic" approach).
Subsequently, a multivariate feature selection is conducted to discover
biomarker candidates. Therefore, either a frequency-based backwards
elimination aproach or ensemble feature selection can be used. PAA provides
a complete toolbox of analysis tools including several different plots for
results examination and evaluation.
I would be very happy to obtain suggestions concerning improvements and any
other feedback. Hence, I would be pleased if you would test PAA and tell
people working with ProtoArrays (or other protein microarrays) about the
Have a lot of fun with BioC 3.0 and PAA!!!
Dipl.-Bioinform. Michael Turewicz
Zentrum für klinische Forschung (ZKF)
Tel.: +49 234 32 29 275
Fax: +49 234 32 14554
E-Mail: <mailto:michael.turewicz at rub.de> michael.turewicz at rub.de
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