[Bioc-devel] biocViews and DNA-methylation

[Sean Davis]

On Tue, Jul 29, 2008 at 2:24 PM, mattia pelizzola
<mattia.pelizzola at gmail.com> wrote:
> Hi,
>
> I'm going to submit to Bioconductor a package for the estimation of
> absolute and relative DNA-methylation levels from MeDIP enrichment
> measures. MeDIP is a methodology based on an antibody specific for
> 5-methyl-Cytosines (Weber et al, 2005).
> I'm confused about the choice of the biocViews  terms. The library has
> been developed based on MeDIP-enrichment measures derived from
> two-channel arrays. Nevertheless, there are people working with it
> with enrichment measures determined by one-channel technologies.
> Moreover, the library is not strictly dependent on microarray data.
> Even next gen sequencing data could be potentially suitable. All that
> is necessary is enrichment measures associated with genomic positions.
> For these reason I do not know if to choose any of the terms related
> to microarray. Also Microarray/CpGIsland is not really appropriate.
> Maybe Technology/Genetics. Is it finally necessary to add new term(s)
> related with epigenetics / DNA-methylation?

Hi, Mattia.  I would include all the terms that might be relevant.
That said, we could consider adding terms for epigenetics or dna
methylation.

Sean