[Bioc-devel] biocViews and DNA-methylation

mattia pelizzola mattia.pelizzola at gmail.com
Tue Jul 29 20:24:02 CEST 2008


Hi,

I'm going to submit to Bioconductor a package for the estimation of
absolute and relative DNA-methylation levels from MeDIP enrichment
measures. MeDIP is a methodology based on an antibody specific for
5-methyl-Cytosines (Weber et al, 2005).
I'm confused about the choice of the biocViews  terms. The library has
been developed based on MeDIP-enrichment measures derived from
two-channel arrays. Nevertheless, there are people working with it
with enrichment measures determined by one-channel technologies.
Moreover, the library is not strictly dependent on microarray data.
Even next gen sequencing data could be potentially suitable. All that
is necessary is enrichment measures associated with genomic positions.
For these reason I do not know if to choose any of the terms related
to microarray. Also Microarray/CpGIsland is not really appropriate.
Maybe Technology/Genetics. Is it finally necessary to add new term(s)
related with epigenetics / DNA-methylation?

Thanks for your help,

mattia



More information about the Bioc-devel mailing list