Dear all,

I am currently using lmer from lme4 package to check for family effect for
a phenotype. Since Family has a genetic as well as environment component, I
would like to look for environment component. For this I would like to look
for phenotypic differences within siblings (which share 50% of genes from
common parents). For example


MourseID    Phenotype    Cage    Family
1    2.1    A       F1
2    4.0    A    F1
3. 1.0    B    F1
4    1.3    C    F2
5    1.9    C    F2
6    4.3    D    F2
7    2.2    D    F2
8    3.4    E    F2
9    3.5    E    F2

Model1 <- lmer(Phenotype ~ 1+ (1|Cage)+(1+Cage/Family)

The model would treat Cage as a separate random variable and Family nested
within Cage (to check for difference between same family from different
cages). I do not know how to formulate the above model to find the
difference within F1 and F2 family mice?

Any idea would be great?

Thanks for your time.

Nicol

	[[alternative HTML version deleted]]

