That is helpful indeed as a starting point. Many thanks!

Angelina

On Thu, Apr 26, 2012 at 4:56 PM, Federico Calboli
<f.calboli@imperial.ac.uk>wrote:

> On 26 Apr 2012, at 16:43, Federico Calboli wrote:
>
> >
> > If each subregion is uniquely identified, so that subregion A can only
> be associated with patient X, and subregion Z can only be found in patient
> Y (and similarly, the same is done for regions), I though that
> >
> > lmer(epression ~ probe + (1|patient) + (1|region) + (1|subregion))
> >
> > would work.  Unique identifiers for the same region in different
> patients might sound odd at first, but in my experience it works and
> simplifies the specification of the nesting, which then happens
> automatically
>
> I might have been too fast in my reply.  It occours to me that if you want
> to have some sort of matching between say, the first region in patient one
> and the first region in patient 2 my advice above won't work.  It will work
> if you do not care about such matching though
>
> F
>
>
>
>
> --
> Federico C. F. Calboli
> Neuroepidemiology and Ageing Research
> Imperial College, St. Mary's Campus
> Norfolk Place, London W2 1PG
>
> Tel +44 (0)20 75941602   Fax +44 (0)20 75943193
>
> f.calboli [.a.t] imperial.ac.uk
> f.calboli [.a.t] gmail.com
>
>

	[[alternative HTML version deleted]]

